As LNCaP, PDB and MDB cell lines can mimic distinct stages of PCa progression [19], we can infer that the Cytoscape network representation of the hK-TFs and the controlled DIhKPs grouped by comparing PDB versus LNCaP, MDB versus LNCaP, MDB and PDB versus LNCaP, and MDB versus PDB could represent proteins associated with different stages of PCa progression (Figure 5). Here, ABR is linked to posterior cortical atrophy.