Unexpectedly, using quantitative western blotting (WB) analysis (Figure 2a), we detected a significant hnRNP K decrease in PBD and MDB cells compared to the parental cell line LNCaP, suggesting its distinct functional role in androgen-resistance compared to PCa where hnRNP K overexpression has shown diagnostic and prognostic value [13]. This evidence concerns the gene HNRNPK and posterior cortical atrophy.