Stratified by APOE ε4 status (Table 4, data for model 1 not shown), higher white wine intake was associated with a higher incidence of AD among APOE ε4 carriers (HR = 1.21; 95% CI: (1.01, 1.46); P = 0.044 for model 2). The gene discussed is APOE; the disease is Alzheimer disease.