Gao et al. [22] showed that c-Myc stimulates glutaminase (GLS) expression through the suppression of miR-23a/b, while the inhibition of Rho-GTPase by a small compound determines the reduction of glutaminase activity, which is dependent of NFκB (nuclear factor kappa-light-chain-enhancer of activated B cells) in breast cancer and B lymphoma cells [52]. The gene discussed is NFKB1; the disease is breast carcinoma.