ACAN and atrial fibrillation: Unlike the results in the Col2a1‐Cre model, the reduction in FOXO expression upon tamoxifen administration in the AcanCreER model was more marked in the NP than in the AF, consistent with higher aggrecan expression in NP than in AF (Anderson & Tannoury, 2005; Boos et al., 2002; Kadow et al., 2015).