CEACAM5 and cancer: In a subcutaneous tumour model, adoptive transfer of carcinoembryonic antigen (CEA) ‐specific CAR‐T cells modestly suppresses tumour growth of CEA‐expressing C15A3 cancer cells but not their parental CEA‐negative MC38 cells.62 In this model, co‐expression of IL‐12 in the CAR‐T cells dramatically enhances the suppressive effects of transferred CAR‐T cells on the C15A3 tumour.