CXCL8 and peripheral neuropathy: Starting from the observation, previously reported by us, that IL-8 signal was responsible for paclitaxel-induced neuropathic pain [21] and with the aim to dissect molecular mechanisms underlying the effects of DSF formulation in counteracting initiation and progression of taxane-induced peripheral neuropathy, we also evaluated direct effects of IL-8-induced signaling in DRG derived neurons cultures.