RUNX1 and myelodysplastic syndrome: Remarkably however, we observed a long median survival for patients with a combination of TET2 and RUNX1 mutations, namely 3.3 years for all patients (n = 11; HR 0.46; p = 0.068) and 5.3 years in MDS INT2/High (n = 6; HR 0.30; p = 0.049), longer than all other cytogenetic or molecular subgroups.