Double staining of blood vessels (CD31) and proliferative cells (Ki67) revealed a lower median count of proliferative tumor endothelial cells (24 [19 31.5] versus 45 [22.5 49], Figure 4C–4F), though it did not reach statistical significance (Mann-Whitney U test: p = 0.175). The gene discussed is MKI67; the disease is neoplasm.