We observed that FOXP3 and miR-155 expression are low in breast cancer cells compared with their expression in normal human breast epithelium and since we show that miR-155 can suppress ZEB2 in human breast cancer cells, we suggest that ZEB2 is tightly regulated by a FOXP3/miR-155 feed forward loop in healthy breast epithelium. This evidence concerns the gene FOXP3 and breast cancer.