Kaplan-Meier analysis indicated strong expression of PKM2 was significantly correlated with the biochemical recurrence of prostate cancer, and the 5-year PSA recurrence-free survival rate was 95.4% in patients with high PKM2 expression compared to 78.8% in their counterparts (p<0.01, Figure 5E). The gene discussed is PKM; the disease is Familial prostate cancer.