The third SSC5 region extended over 2 Mb (between 55 and 57 Mb), with the best SNP located within the PLEKHA5 (Pleckstrin Homology Domain Containing A5) gene (DRGA0005864, p-value = 1.99 × 10–5), recently described as a mediator of distant melanoma metastasis in the brain [42]. Here, PLEKHA5 is linked to melanoma.