IL2 and breast neoplasm: In one study, γδTc TIL isolated from a breast tumor were expanded in high levels of IL-2 for several weeks prior to immunosuppression assays and proved to inhibit dendritic cell maturation and CD8+ T cell cytotoxicity (56); however, given the known functional plasticity of γδTc, such assays conducted on ex vivo expanded cells removed from the TME cannot inform the function of γδTc in situ.