SPP1 and glioma: Gene Ontology term “Regulation of cell adhesion” consisted of genes which roles in the glioma progression were widely studied: Il10, Mmp14, and Spp1. Interestingly, upregulation of all of the three genes was found only for the murine CD11b+ GAMs, IL10 and SPP1 were also found in CD14+ human GAMs and MMP14 in CD11b+ human GAMs.