Interestingly, in the cardiac myocardial infraction or coronary artery disease model, ATG14 is required for the angiogenesis via Becn1–Vps34–ATG14 complex (Lu et al., 2016), which is a novel agent for treatment of acute ischemia-mediated myocardial injury via handling revascularization. The gene discussed is ATG14; the disease is coronary artery disorder.