The upper panel of Fig. 1 shows the association between LAEF and LAVImax after multivariable adjustment for age, sex, smoking, body mass index, diastolic blood pressure, diabetes, previous myocardial infarction, previous TIA/stroke, LVEF, LV mass index, moderate valvular disease and NT‐proBNP. The gene discussed is NPPB; the disease is myocardial infarction.