As mentioned earlier, diets containing high amounts of salt and cholesterol have beenimplicated to be a major risk factor in multiple neurodegenerative disorders.Apolipoprotein E (ApoE) is the cholesterol transporter in the body which isresponsible for the maintenance of lipid and cholesterol homeostasis in the body.Studies have indicated a connection between the ApoE4 allele on the apolipoproteingene with hypercholesterolemia and increased risk of development ofAlzheimer’s disease [16]. This evidence concerns the gene APOE and Hypercholesterolemia.