Hsa_circ_091692 is encoded by the CD99L2 (CD99‐Like 2) gene, the protein product expressed on leucocytes and play an important role in various acute and chronic inflammatory diseases.19 Hsa_circ_102296 aligns with ANKRD12 (Ankyrin repeat domain 12), which encodes a 224 kD nuclear protein associated with colorectal cancer.20 Hsa_circ_029965 is derived from PDS5B, and its encoded protein is related to chromosome segregation.21 On the other hand, hsa_circ_103571 was down‐regulated in active TB plasma. The gene discussed is CD99L2; the disease is colorectal cancer.