Compared with control subjects, NSCLC patients had significantly higher levels of plasma IgG for CD25a (Z = −8.05, P < 0.001) and FOXP3 (Z = −4.17, P < 0.001), lower levels for CD25b (Z = −3.58, P < 0.001), and a trend toward lower levels for CD25c (Z = −1.70, P = 0.09). Here, FOXP3 is linked to non-small cell lung carcinoma.