PRRT2 and non-small cell lung carcinoma: Similarly, Yang et al. [25] demonstrated that CK2α- and PKC-induced phosphorylation of rpS3 and TNFR-associated factor 2 (TRAF2) granted NSCLC cells radioresistance by activating the NF-κB signaling pathway; however, CK2α- and PKC-deficient NSCLC cells are radio-responsive.