Indeed, several beneficial metabolic effects of the Mediterranean diet, rich in olive oil, are linked to high oleic acid ingestion [10], and the intake of a diet enriched in Monounsaturated Fatty Acids (MUFAs) increases plasma GLP-1 levels and improves glycemic control in diabetes type 2 and insulin-resistant patients [11]. Here, GLP1R is linked to type 2 diabetes mellitus.