TRIM26 and nasopharyngeal carcinoma: In addition to low immune response, a more extensive dysregulation of gene expressions was observed in NPC patients with reduced TRIM26. Despite no support available from further clinical and experimental data, these results are heuristic for understanding the association of TRIM26 with NPC susceptibility; low immune response and extensively dysregulated gene expression owing to TRIM26 downregulation probably confer a high susceptibility to NPC.