In the past, Xiong et al45 found that the expression of TRIM26 mRNA in nontumor NP epithelial tissues was significantly higher than that in NPC, suggesting that TRIM26 gene plays an important role in the development of nasopharyngeal carcinoma, which may be a tumor suppressor gene of nasopharyngeal carcinoma. The gene discussed is TRIM26; the disease is nasopharyngeal carcinoma.