YWHAQ and renal fibrosis: In term of studies regarding the 14‐3‐3σ isoform in kidneys, not much is known, except for its involvement in renal cell carcinoma; cell culture studies demonstrated that when a specific mutant Von Hippel‐Lindau protein is expressed, 14‐3‐3σ is down‐regulated.36 However, no other studies exist on the role of 14‐3‐3σ in other pathological processes in the kidney, like renal fibrosis.