14‐3‐3 proteins play crucial role in a wide range of cellular activities, including cell proliferation, protein trafficking, DNA replication, cell apoptosis and survival.8, 9 This family of proteins has been involved in numerous neurological disorders while some members of the family such as 14‐3‐3ζ, 14‐3‐3γ and 14‐3‐3σ are associated with a variety of human cancers.10, 11 However, their role in the process of renal pathologies was not studied so far. The gene discussed is YWHAQ; the disease is nervous system disorder.