ATF4 and Parkinson disease: NEF2L2, the gene coding for Nrf2, a protein involved in the oxidative stress response (Shih et al. 2005); ATF4, previously found altered by rotenone and involved in cell stress and proteasome inhibition (Krug et al. 2014; Smirnova et al. 2016); and EAAC1, responsible for glutamate uptake and found to be downregulated in PD models (Kinoshita et al. 2014; Zhang et al. 2016a, b).