FOLR2 and colorectal carcinoma: MAPK6-TMOD3, with different direction and junction point from TMOD3-MAPK6, was identified by Hu et al.20 In our study, we confirmed expression of RNF121-FOLR2 in HT-29 cells, which was contrary to Nome et al. who identified expression of fusion genes via RNA-seq of various CRC cell lines, including HT-29.21 The discrepancy may be due to the low expression of RNF121-FORL2 in HT-29 cells, which may result in significantly fewer mapping reads by RNA-seq.