EML4 and colorectal carcinoma: In comparison, Kloosterman et al. reported that only 2.5% of CRC expressed fusion genes, including ArfGAP with GTPase domain, ankyrin repeat, and PH domain 3 (AGAP3)-BRAF, TRIM24-BRAF, discs large MAGUK scaffold protein 1 (DLG1)-BRAF, echinoderm microtubule associated protein like 4 (EML4)-NTRK3, ribosome binding protein 1 (RRBP1)-RET, USP9X-embryonic stem cell-expressed Ras (ERAS), and eukaryotic translation initiation factor 3 subunit E (EIF3E)-RSOP2 fusion genes.8 These discrepancies may be due to differences in sample collection and preparation and bioinformatics analysis pipeline.