BTRC and cancer: BTYNB may restrain binding of IGF2BP1 to the coding region stability determinant of c-Myc mRNA and downregulate several mRNA transcripts including c-Myc, β-TrCP1, and eEF2 both in IGROV-1 and SK-MEL2 cancer cells, as well as decrease activation of nuclear transcriptional factors-kappa B (NF-κB).