CRYAA and neoplasm: The overall trend indicates that HSPs were highly expressed in tumour samples (one-sided Mann-Whitney U test P val = 1.256e− 10), nevertheless, a more detailed study showed a group of six genes (DNAJB8, DNAJC5G, DNAJB3, ODF1, CRYAA, and HSPB3) with very low expression levels in almost all the samples and was not detected in at least 50% of the cohort or more.