Literature survey shows that most of DEPs identified by our methods were previously reported to be related to liver cancer, for example, p53 signaling pathway (p-value = 0.012), transcriptional misregulation in cancer (p-value = 0.003), and hepatitis B (p-value = 0), which are likely differentially expressed between recurrent and non-recurrent liver cancer. The gene discussed is TP53; the disease is hepatitis B virus infection.