Specifically, patients with the mutations c.1605_1606delTG (p.Ser535SerfsX3) and c.3927_3931delAAAGA (p.Glu1309AspfsX4) were affected with FAP and desmoid tumors, developed after restorative proctocolectomy, consistent with previous reports [27] (Figure 2a–b). This evidence concerns the gene FAP and desmoid tumor.