VCAM-1 was also partially correlated with cIMT in RA patients undergoing Infliximab therapy, but this was not evident for carotid plaques or other biomarkers of endothelial cell activation, even though anti-TNF treatment seems to reduce the serum levels of ICAM-3 and P-selectin molecules [122,123]. The gene discussed is TNF; the disease is rheumatoid arthritis.