TNFRSF8 and classic Hodgkin lymphoma: NLPHL and cHL are morphologically and immunophenotypically distinct; the tumour cells of NLPHL, known as lymphocytic and histiocytic (L&H) cells, are often negative for classical HL markers (e.g., CD15, CD30), but express B-cell markers, including CD20 and CD19, which are absent from the HRS cells of cHL [13].