In nerve cells, Tau is typically found in axons, but in the tauopathies, such as AD, progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), or inherited frontotemporal dementia and Parkinsonism linked to chromosome 17 (FTDP-17), this protein is present in an abnormal filamentous form and redistributed to the cell body and neurites [46]. This evidence concerns the gene MAPT and Classical progressive supranuclear palsy.