TGM3 and metastatic malignant neoplasm in the lymph nodes: Overall survival was significantly associated with expression of TGM-3 (p<0.024) and response to chemo-radiotherapy treatment (p<0.000) as shown in “Fig 2D and 2E.” Other factors viz age, sex, tumour stage, differentiation, lymph node metastasis and adverse oral habit did not have statistical significant correlation with overall survival.