Fig 8B shows one case of a classic papillary thyroid carcinoma with a few granulocytes scattered throughout the tumor tissue. An isotype-matched unrelated antibody yielded negative results (not shown). A high CD66b+ cell count was significantly associated with a larger tumor volume (p = 0.04, Table 1 and Fig 8C). Thus, PMN density positively correlated with larger tumor size in TC (r = 0.43, p = 0.01; Table 1 and Fig 8D). No correlations between PMN infiltration and other clinical parameters were found (Table 1). This evidence concerns the gene CEACAM8 and thyroid gland papillary carcinoma.