TXNIP and Stroke: "In order to determine the contribution of both genetic TXNIP-deletion (TKO) and the pharmacologic TXNIP inhibition with RES on outcome/recover after embolic middle cerebral artery occlusion (eMCAO) stroke, the total 64 mice (WT and TKO) were separated into following groups: WT mice subjected to sham operated control + vehicle treatment group I (sham only); WT mice subjected to eMCAO + vehicle treatment group II (WTeMCAO only); WT mice subjected to eMCAO + RES (5mg/kg) treatment group III (WTeMCAO + RES only) and TKO mice subjected to eMCAO group + vehicle treatment IV (TKO-eMCAO only)." [20]