Disease features of diabetic liver studies in hamsters model the situation in humans, with well-known pathological changes, including steatosis, fibrosis, elevated levels of liver enzymes, necrosis of hepatocytes, biliary hyperplasia, up-regulated expression of TNF-α and NF-κB, oxidative stress, and liver dysfunction [18, 32]. The gene discussed is TNF; the disease is digestive system neoplasm.