Among the strongest 10 associations with LN among South Europeans, there was enrichment for TRIM protein coding genes (p = 2.1E-10) such as TRIM26 (p = 2.2E-05), TRIM31 (p = 4E-05) and TRIM40 (p = 6E-05) (S4 Table). Here, TRIM31 is linked to lobular neoplasia.