Of note, many of these top SNPs are risk alleles for CKD and not SLE, such as ETV4 and GCKR in Hispanics, NFATC1 and SYPL2 in African Americans, DAB2 and KBTBD2 in Asians, and PRKAG2 in South Europeans. This evidence concerns the gene SYPL2 and systemic lupus erythematosus.