Within each cancer type, these mutations often occur in the same gene, either in separate individuals or in the same individual, with the highest counts occurring in ZNF721 in UCEC (17 mutations, 14 individuals) and COAD/READ (11 mutations, 8 individuals), and ZNF208 in SKCM (32 mutations, 17 individuals). The gene discussed is ZNF208; the disease is cancer.