A previous report showed that there was no significant difference in the frequency of the recurrent between anti-SFPQ Ab-positive (n = 27) and -negative (n = 24) patients with anti-MDA5 Ab-positive DM, but all 5 anti-MDA5 Ab-positive patients who showed the recurrence were anti-SFPQ Ab-positive.[24] Our patient's case may suggest an association between the recurrent and the appearance of anti-SFPQ Ab. The gene discussed is SFPQ; the disease is dermatomyositis.