SLC5A5 and cancer: Otherwise, with transfer of the NIS gene into cells without NIS gene expression (such as therapeutic cells: cytotoxic T or natural killer cells; or Dedifferentiated cancer cells, etc.), the NIS-expressing cells can be imaged by radionuclide-based molecular imaging techniques using gamma ray or positron-emitting radiotracers and be cleared by beta or alpha particle-emitting radionuclides [3].