Among exosomal proteins evaluated for their potential diagnostic value, PSMA, PSA, PTEN, survivin, p-gp, claudin3, FABP5, gammaglutamyl transferase, EGFR, ITGA3, ITGB1, TM256, and TGM4-ADSV were found elevated in the blood (plasma or serum) or the urine from prostate cancer patients (25, 35, 36, 48, 53, 54, 142, 151, 178, 181, 187–189) (Table 2). The gene discussed is KLK3; the disease is Familial prostate cancer.