Hoque et al. (2008) reported that apoptosis of PCa cells was induced by lovastatin and simvastatin through both cytochrome c-dependent and -independent signaling pathways, involving caspase 3, 8, and 9. Statins may sensitize cells to radiation by arresting cell cycle in the late G1 phase (Chan et al., 2003). Here, CASP3 is linked to posterior cortical atrophy.