LGALS2 and Insulin resistance: Interestingly, in a search for genes associated with insulin resistance, a genotype of galectin-2, LGALS2 rs7291467, was stronger associated with changed fasting plasma glucose and serum insulin than other alleles were [26], and the same genotype which has a single-nucleotide polymorphism (3279C → T) in intron 1 of LGALS2 encoding galectin-2 was previously found to be significantly associated with myocardial infarction [27].