In these pathways 6 genes were related to cancer like pancreas cancer (Ramp1 and Cckbr)16,18,19, melanoma (Plcb4)20, cervical and ovarian (Adcyap1 and Trpc3)21,22, and colorectal cancer (Ptger3)23. The gene discussed is PTGER3; the disease is pancreatic neoplasm.