As shown inFigure 1A and B, the serum mRNAand protein levels of IL-33 were elevated in the CRC mice when compared with WT mice(P < .05; P < .05, respectively); the mRNA andprotein levels of sST2 or ST2L in the serum were elevated in CT26 tumor-bearing mice whencompared to WT mice (P < .05; P < .05,respectively; Figure 1C-E). Here, IL33 is linked to neoplasm.