Intriguingly, the expression of Nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) target genes (Bcl2a1, Nfkb2, and CCR7) was significantly decreased in the Rictor-depleted circulating T-ALL cells, whereas selected FoxO1/3 target genes (Il7ra, Sell, and S1p1) were not [53]. Here, RICTOR is linked to acute lymphoblastic leukemia.