Specific siRNA‐mediated RXFP1 KD in patient GBM‐1 and U87MG with two different siRXFP1‐1/2 constructs abolished the ability of CTRP8 to cause STAT3 phosphorylation in patient GBM (Fig. 1C; Fig. S1B) and U87MG (Fig. 1D). The gene discussed is RXFP1; the disease is glioblastoma.