MGMT and glioblastoma: Our data showed that the DNA protective role of CTRP8 was as effective in MGMT‐negative U87MG and MGMT‐positive patient GBM cells (Thanasupawat et al., 2017a), excluding altered cellular MGMT enzyme levels as a target of activated RXFP1 and cause for the CTRP8‐mediated protection against TMZ‐induced DNA damage in our GBM models.