We also previously identified lysosomal cathepsins as targets of H2 relaxin, the cognate ligand of RXFP1, and CTRP8 in human thyroid cancer (cathepsin‐D and cathepsin‐L) and GBM (cathepsin‐B), respectively (Glogowska et al., 2013; Hombach‐Klonisch et al., 2006). The gene discussed is RXFP1; the disease is thyroid gland carcinoma.