For example, 5 point mutations in the genes encoding synuclein alpha (SNCA; A53T, A30P, E46K, H50Q, and G51D) and 52 mutations (alzforum.org/mutations) in amyloid precursor protein (APP) have so far been identified to be associated with PD and AD, respectively [2, 3]. This evidence concerns the gene APP and Alzheimer disease.