BMAL1 expression also positively correlates with patient survival in pancreatic ductal adenocarcinomas (61), causes growth inhibition in lymphoma/leukemia cells (58), negatively impacts DNA-repair capacity of mice fibroblast (73), but promotes proliferation in malignant pleura mesothelioma (74), suggesting that its role in tumorigenesis is complex and tissue-specific. The gene discussed is BMAL1; the disease is leukemia.