CXCL10 and neoplasm: CXCR3A is the major chemokine receptor found on T lymphocytes and NK cells, and plays a critical role in the development of anti-tumor immunity and inhibits angiogenesis, which is relevant to a variety of tumors [31], whereas CXCR3B mediates the angiostatic activity of CXCL10 on human microvascular endothelial cells [32].