8-Isoprostane, a biomarker of oxidative stress, myeloperoxidase and eosinophil cationic protein, are also increased in the bronchoalveolar lavage fluid (BALF) of IPF patients (Montuschi et al., 1998; Kliment and Oury, 2010). Here, RNASE3 is linked to idiopathic pulmonary fibrosis.